Starring:
- Harlem Globetrotters
- Billy Brown
- Dorothy Dandridge
- Thomas Gomez
- Bill Walker
- Roscoe Cumberland
- William 'Pop' Gates
- Marques Haynes
- Louis 'Babe' Pressley
- Ermer Robinson
- Ted Strong
- Reece 'Goose' Tatum
- Frank Washington
- Clarence Wilson
- Inman Jackson
Abe Saperstein is the manager and coach of the Harlem Globetrotters. An all-American collegiate basketball player, Billy Townsends, wants to quit college and join the team, but Abe thinks Billy isn't ready for professional basketball and advises him to stay in school. Against Abe's advisement, Billy drops out of school and earns a contract to play with the Globetrotters and marries his college sweetheart Ann Carpenter. However, an injury to Billy's knee during a game causes the young basketball player to make some decisions that would eventually lead him to get fired from the team.